Multiple Sclerosis (MS)

Figure 1: Sagittal T2 (top row left), sagittal T1 post-contrast fat-saturated (FS) (top row right), and axial T2 images (middle row left) of the cervical spine demonstrate short segment (<2 vertebral bodies in length), T2 hyperintense lesions in the peripheral aspect of the spinal cord with variable enhancement. Axial T1 post-contrast (middle row right) and axial T2FS (bottom row) images of the brain demonstrate a T2 hyperintense lesion in the left frontal periventricular white matter with an incomplete ring of enhancement. The length of the lesions in the cervical spinal cord and the enhancement pattern and location of the lesion in the brain are most compatible with Multiple Sclerosis.

 

Figure 2: Coronal T2FS (top row left), coronal T1 post-contrast fat-saturated (FS) (top row right), and axial T1 post-contrast FS images (middle row left) through the orbits demonstrate a short segment T2 hyperintense lesion with associated enhancement in the left optic nerve. Sagittal STIR (middle row right), sagittal T1 post-contrast FS (bottom row left), and axial T2 images (bottom row right) of the cervical spine demonstrate an enhancing, short segment (<2 vertebral bodies in length), T2/STIR hyperintense lesion in the peripheral aspect of the spinal cord. The differential diagnosis includes both Multiple Sclerosis and Neuromyelitis Optica. However, the length of the lesion in both the spinal cord and optic nerve favor multiple sclerosis. The patient’s CSF demonstrated oligoclonal...

Top