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Choroid Plexus Carcinoma (CPC)

Last Updated: October 1, 2018

Figure 1: Axial FLAIR (left) and sagittal T1WI post contrast (right) demonstrate a lobulated, intraventricular enhancing tumor. This choroid plexus carcinoma is indistinguishable from choroid plexus papilloma given its lack of invasive features.

 

Figure 2: This choroid plexus carcinoma is quite large. As with many tumors of this size, the intraventricular origin of this tumor is difficult to determine. The cleft of hyperintense surrounding CSF on T2WI (left) can give a clue. The tumor demonstrates less enhancement on postcontrast T1WI (right) than is usually present in choroid plexus tumors.

Basic Description

  • Malignant, rapidly-growing intraventricular tumor arising from choroid plexus epithelium
  • Less common than CPP

Pathology

  • WHO grade III
  • Hypercellularity, pleomorphism,...