Figure 1: This inferior right temporal ganglioglioma is nearly invisible on T1WI (top row left). The cystic change seen in this lesion on coronal T2WI (top row right) and contrast-enhanced T1WI (bottom) is variably present in this type of lesion. The degree of enhancement is also highly variable, though avid in this patient's lesion.
Figure 2: This complex FLAIR hyperintense (top row left), STIR hyperintense (top row right) gangliogliomain the left frontal lobe demonstrates areas of low signal intensity hemorrhage medially (an atypical feature) and only a small amount of brighter surrounding edema anteriorly on FLAIR (top row left). Cystic change are also present in the periphery, most clearly visible on STIR (top row right). Only faint enhancement is present in this example (bottom row left - axial contrast, bottom row right - coronal contrast).
Figure 3: This ganglioglioma involves the medial right frontal lobe in a display of FLAIR hyperintensity (top row left) without any appreciable contrast enhancement (top row right). The lesion is typical in its infiltrative involvement of the cortex and adjacent white matter. There is no restricted diffusion (bottom row left – DWI, bottom row right – ACD) to suggest hypercellularity.
- Slow-growing, well-differentiated, and cortically-based neuroglial tumor
- WHO grade I or II
- Anaplastic ganglioglioma (WHO III) rare
- Dysmorphic ganglion and glial cells