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Corpus Callosotomy

Last Updated: January 16, 2020

Introduction

The surgical treatment of epilepsy includes 2 different types of procedures, resection of the seizure focus and palliative techniques such as disconnection and neurostimulation. For those patients without an epileptogenic seizure focus, interhemispheric disconnection with a corpus callosotomy is a palliative attempt to alleviate intractable epilepsy. Therefore, the goal of performing a callosotomy is not to cure a patient's seizure disorder but, rather, to reduce the frequency of seizures and resultant morbidity. Performing a callosotomy functionally isolates the nonepileptogenic hemisphere in hope of preventing secondary generalization.

The corpus callosum serves as the principal commissure providing interhemispheric communication within the brain and is divided into 4 part...