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Cerebral Amyloid Angiopathy (CAA)/Amyloidoma

Last Updated: October 1, 2018

Figure 1: These images demonstrate T1 hypointense (top row left), FLAIR hyperintense (top row right) signal within the left parietal white matter radiating medially to the ventricular wall with irregular, somewhat serpiginous enhancement (middle row left). There was no reduction in diffusivity on DWI/ADC images (middle row right and bottom row).

Description

  • Cerebrovascular disorder characterized by the deposition of amyloid protein in the media and adventitia of small and medium-sized vessels of the cerebral cortex, subcortical white matter and leptomeninges

Pathology

  • Unclear
  • Thought to be related to a benign clonal proliferation of plasma cells
  • Three varieties
    • Cerebral amyloid angiopathy, amyloidoma, rare inflammatory subtype

Clinical Features

  • Symptoms
    • Seizures...