Figure 1: Here we present an HIV patient with low CD4 count who was not taking HAART around the time of imaging. These images demonstrate at least two T1 hypointense (top row left), FLAIR hyperintense (top row right) lesions centered within the left parietal cortex and left basal ganglia. Both lesions demonstrate punctate, central restricted diffusion (middle row). The lesion in the left parietal cortex has a rim of thick enhancement (bottom row left) and there is minimal associated susceptibility artifact (bottom row right) likely reflecting microhemorrhage.
- Most commonly caused by Candida albicans, though glabrata and parasilosis are also common
- CNS infection almost always caused by hematogenous spread with disseminated systemic infection