Vols. Videos

Bacterial Abscess

Last Updated: October 1, 2018

Figure 1: MRI demonstrates multiple FLAIR hyperintense lesions with primarily central reduced diffusivity with spread into the posterior horns of the lateral ventricles (best demonstrated on the DWI and FLAIR sequences). The central location is fairly classic and suggests a systemic cause of the infection. 

Description

  • Focal infection that begins as an area of cerebritis and develops into a collection of encapsulated pus
  • Mechanisms:
    • Direct inoculation and hematogenous spread

Pathology

  • Britt and Enzmann classification
  • Early cerebritis (1st-4th day)
    • Ill-defined focal infection
  • Late cerebritis (5th-10th day)

    • Undergoes central necrosis and vascular proliferation
  • Early capsule (10th-14th day)

    • Develops a well-defined capsule
  • Late capsule (2 weeks to months)

    • Thicke...