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Tuberous Sclerosis

Last Updated: October 1, 2018

Figure 1: Multiple FLAIR-hyperintense (top row left) subependymal nodules with corresponding dark susceptibility artifact (top row right) that reflects calcification. These nodules are also clearly visible on the T2 image (middle row left) against the bright CSF. A few of the nodules demonstrate moderate enhancement (middle row right). Also, notice the much larger heterogeneous lesion along the right lateral ventricle at the level of the caudothalamic groove compatible with a subependymal giant cell astrocytoma.

Additionally, there are numerous regions of cortical expansion with T2/FLAIR hyperintense signal (middle row left, bottom row left) and associated, increased linear signal radiating from the periventricular white matter to the subcortical regions (bottom row right) – known as th...