Vols. Videos

Teratoma

Last Updated: October 1, 2018

Figure 1: This complex pineal-region teratoma demonstrates areas of solid and cystic change and calcification on CT (top left) and areas of hyperintense fat signal intensity on the T1-weighted MR image (top right). Heterogeneous enhancement is a hallmark finding that illustrates the complexity of teratomas on T1 after contrast administration (bottom).

Basic Description

  • Midline intracranial tumor arising from multipotential germ cells

Pathology

  • Contains tissue from all three germ cell types: ectoderm, endoderm, and mesoderm
    • Fat, calcification, teeth, soft tissue, sebaceum, and cysts
  • Three types

    • Mature: well-differentiated, WHO grade 1, often with cystic tumor component
    • Immature: intermediate differentiation
    • Malignant: malignant degeneration of immature teratoma, may co...