Vols. Videos

Histoplasmosis

Last Updated: October 1, 2018

Figure 1: Multiple lesions scattered throughout the parenchyma demonstrating T1 hypointensity (top row left) and T2/FLAIR hyperintensity (top row right, second row left) with a rim of edema and a thin rim of enhancement (second row right). As is typical in fungal infections, the periphery demonstrates restricted diffusion (third row left, third row right), but not the center of the necrosis. SWI (bottom row) also demonstrates mild dark susceptibility artifact in the periphery of these lesions likely representing a combination of heavy metal deposition and microhemorrhage.

Description

  • Caused by dimorphic fungus Histoplasma Capsulatum
  • Exists as a mold in the environment and yeast at body temperatures
  • Endemic to Midwest
  • Disseminated disease is uncommon and occurs primarily when there...