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Anteromedial Temporal Lobectomy

Last Updated: September 30, 2018

Technical Principles of Temporal Lobectomy and Amygdalohippocampectomy

The estimated prevalence of epilepsy in North America is 5 to 10 cases per 1000 people, and approximately one-third of those with epilepsy fail to achieve adequate seizure control with antiepileptic drugs or are unable to tolerate the side effects required to do so. A large body of evidence indicates that failure to adequately control seizures impairs cognition, decreases overall quality of life, and increases mortality.

Medical intervention is the first step in treating epilepsy. Despite the use of various antiepileptic drugs, when medical therapy fails to achieve seizure freedom, comprehensive surgical evaluation is appropriate. The most common and well-characterized focal epilepsy syndrome is medial (mesial) temp...