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Evaluation of Cavernous Malformations

Last Updated: September 28, 2018

Cavernous malformations (CMs) are benign, well-circumscribed vascular anomalies of the blood vessels of the brain and spinal cord. Several terms have been used for cavernous malformations, including cavernous hemangiomas, cavernous angiomas, and cavernomas.

CMs, along with capillary telangiectasias, arteriovenous malformations, and developmental venous anomalies (DVAs), make up the four categories of cerebral vascular malformations. CMs compose 5% to 13% of central nervous system (CNS) vascular malformations and occur in 0.02% to 0.5% of the population.

These dilated capillary vessels have an increased risk of focal hemorrhage, leading to seizures and focal neurologic deficits. The locations of CNS CMs occur proportionally to the CNS tissue volume, with 80% in the supratentorial space, 1...