Figure 1: Harvey Cushing’s career in neurosurgery was initially founded on the surgical management of pituitary tumors. In the absence of adequate imaging, functional adenomas were more likely to be diagnosed and surgically explored. In my review of ~15,000 patient photographs in the Cushing Brain Tumor Registry, these are the only two photos in which Cushing himself is included. The patient on the left was diagnosed with acromegaly and the one on the right may have suffered from progeria.
Acromegaly: Principles of Microadenomectomy
Diagnosis and Evaluation
Pituitary tumors are diverse—they range from nonfunctional to functional and from millimeters to centimeters. The majority of functional adenomas overproduce one or more of the pituitary hormones, which may be prolactin, growth...