Chordoma and Chondrosarcoma
Last Updated: February 18, 2020
Chordomas of the cranial base are commonly extradural, deriving from the clivus centrally, but rare intradural extension is possible. Chondrosarcomas originate along the paramedian central skull base from embryonic mesenchymal remnants and occupy the petrosphenoclival junction, with the majority centered at the temporo-occipital junction.
Both chordomas and chondrosarcomas are rare lesions and represent less than 1% of all intracranial tumors. Metastasis is possible and is associated with advanced local d...