Vols. Videos

Glomus Vagale Paraganglioma (GVP)

Last Updated: October 1, 2018

Figure 1: T1WI (top row left) demonstrates a low signal intensity mass in the typical location of the vagus nerve along the carotid space. The lesion can be easily mistaken for a lymph node. As with other paragangliomas, these lesions are typically hyperintense with salt-and-pepper vascular flow voids on T2WI (top row right) and avidly enhancing on postcontrast T1WI (bottom).

Basic Description

  • Benign, hypervascular neuroendocrine tumor of neural crest origin
  • Less common than glomus caroticum (carotid body tumor) and glomus jugulare

Pathology

  • Arises from glomus bodies within CN 10 nodose ganglion
  • Composed of chemoreceptor cells of neural crest origin
  • Arterial supply from the ascending pharyngeal artery
  • Familial or sporadic
    • Associated with NF-1, MEN-2, and von Hippel-Linda...