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Gliomatosis Cerebri

Last Updated: October 1, 2018

Figure 1: This diffuse infiltrative glioma was described as gliomatosis cerebri under previous classification systems. Note the diffuse FLAIR (top row) involvement of the right temporal lobe, posterior right frontal lobe, right insula, right basal ganglia and right thalamus. No enhancement is present in this lesion on T1WI after contrast administration.

Basic Description

  • Uncommon, diffusely infiltrating tumor of glial origin involving a large amount of brain parenchyma (previously 3 lobes to meet gliomatosis criteria)


  • This tumor type has been deleted from the 2016 WHO Classification
  • A tumor previously described as Gliomatosis Cerebri would now be classified as a diffuse type of astrocytoma, oligodendroglioma, or glioblastoma

Clinical Features

  • Affects all ages (40...