Vols. Videos

Rosette-Forming Glioneuronal Tumor (RGNT)

Last Updated: October 1, 2018

Figure 1: This mildly complex, circumscribed T2-FLAIR hyperintense rosette-forming glioneuronal tumor fills and expands the fourth ventricle (left), contributing to hydrocephalus in this patient, but causes little edema. The tumor demonstrates a heterogeneous internal pattern of enhancement (right).

Basic Description

  • Uncommon, slow-growing, and benign tumor usually arising in the posterior fossa

Pathology

  • WHO grade I
  • Composed of pseudorosette-forming neurocytes and astrocytes
  • No malignant transformation

Clinical Features

  • Affects young adults (mean 30 years old)
  • Female gender predilection (2:1)
  • Commonly presents with signs/symptoms of increased intracranial pressure secondary to obstructive hydrocephalus
    • Headache, nausea, ataxia, vertigo
  • Treatment: surgical resectio...