White matter dissection of the lateral cerebrum.  The cerebral cortices have been removed to reveal the underlying white matter pathways.  Abundant U-shaped cortico-cortical (short associational) fibers connect adjacent gyri with one another. The arcuate fasciculus, a more substantial C-shaped fiber bundle, connects the inferior frontal lobe with the posterior temporal and inferior parietal lobes, and plays a critical role in language function.  The temporal and frontal opercular cortices have been removed to reveal the insular cortex on the medial wall of the lateral fissure of Sylvius (Image courtesy of PA Rubino)