Coronal section through the brain at the level of the foramen of Monro. The "central core" of the cerebral hemisphere is the deep area of the cerebrum located between the insula and the midline. Central core structures from lateral-to-medial include the insular cortex, extreme capsule (composed of short association fibers connecting the insular and opercular cortices), claustrum, external capsule (which is divided into a dorsal external capsule or claustrocortical fibers, and a ventral external capsule which comprises the uncinate fasciculus and the inferior frontoccipital fasciculus), putamen, lateral medullary lamina, globus pallidus (divided by the medial medullary lamina into globus pallidus interna and externa), and internal capsule. The internal capsule is a collection of projection fibers that interconnects the cortex with  subcortical structures such as the basal ganglia, thalamus, brainstem and spinal cord.   The internal capsule joins the external capsule just superior to the lenticular nucleus to form the corona radiata. The cingulate gyrus, a component of the limbic system, is located dorsal to the corpus callosum.  The latter is a major commissural fiber bundle that interconnects reciprocal areas of the left and right cerebral hemispheres. (Image courtesy of PA Rubino)